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Bioinformatics


BLAST
Cister
ClustalW
ClustalX
Comet
Dotter
FASTA
fastDNAml
GeneMachine
GENSCAN
HMMer
HMMgene
MrBayes
MZEF
PHRED/PHRAP/Consed
PHYLIP
ReadSeq
RepeatMasker
SEG
sim4
Sputnik
Treetool


BLAST

National Center for Biotechnology Information

BLAST is the Basic Local Alignment Search Tool. It is a set of search programs designed to explore all available sequence databases in either protein or DNA. This software has been designed to achieve great speeds while keeping a well-defined statistical interpretation.

BLAST is available on the following HPC machines:

Machine Version Instructions Last Update

Hammer

2.2.15

http://gears.aset.psu.edu/hpc/software/bioinf/blast

09-Nov-2006

LION-XB

2.2.15

http://gears.aset.psu.edu/hpc/software/bioinf/blast

09-Nov-2006

LION-XC

2.2.15

http://gears.aset.psu.edu/hpc/software/bioinf/blast

29-May-2007

LION-XL

2.2.8

http://gears.aset.psu.edu/hpc/software/bioinf/blast

07-Oct-2004

LION-XM

2.2.8

http://gears.aset.psu.edu/hpc/software/bioinf/blast

03-Nov-2004

LION-XO

2.2.15

http://gears.aset.psu.edu/hpc/software/bioinf/blast

09-Nov-2006

Unisys

2.2.11

http://gears.aset.psu.edu/hpc/software/bioinf/blast

02-Apr-2007

Versions listed in bold are the default version.


Cister

Martin Frith

Cister predicts regulatory regions in DNA sequences by searching for clusters of cis-elements.

Cister is available on the following HPC machines:

Machine Version Instructions Last Update

Hammer

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/cister

09-Nov-2006

LION-XB

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/cister

09-Nov-2006

LION-XC

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/cister

29-May-2007

LION-XL

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/cister

07-Oct-2004

LION-XM

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/cister

09-Nov-2006

LION-XO

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/cister

09-Nov-2006

Versions listed in bold are the default version.


ClustalW

Institut de Genetique et de Biologie Moleculaire et Cellulaire

ClustalW is a general purpose multiple alignment program for DNA or proteins.

ClustalW is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

1.82

http://gears.aset.psu.edu/hpc/software/bioinf/clustalw

07-Oct-2004

LION-XM

1.82

http://gears.aset.psu.edu/hpc/software/bioinf/clustalw

03-Nov-2004

Versions listed in bold are the default version.


ClustalX

Institut de Genetique et de Biologie Moleculaire et Cellulaire

Clustal X is a general purpose multiple alignment program for DNA or proteins, using a window interface for sequence input and display.

ClustalX is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

1.81

http://gears.aset.psu.edu/hpc/software/bioinf/clustalx

07-Oct-2004

LION-XM

1.81

http://gears.aset.psu.edu/hpc/software/bioinf/clustalx

03-Nov-2004

Versions listed in bold are the default version.


Comet

Martin Frith

Comet finds statistically significant clusters of cis-element motifs in a DNA sequence.

Comet is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/comet

07-Oct-2004

LION-XM

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/comet

03-Nov-2004

Versions listed in bold are the default version.


Dotter

Karolinska Institutet Center for Genomics Research

Dotter is a graphical dotplot program for detailed comparison of two sequences.

Dotter is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

3.0

http://gears.aset.psu.edu/hpc/software/bioinf/dotter

07-Oct-2004

LION-XM

3.0

http://gears.aset.psu.edu/hpc/software/bioinf/dotter

03-Nov-2004

Versions listed in bold are the default version.


FASTA

National Center for Biotechnology Information

No product description available.

FASTA is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

3.4t10

http://gears.aset.psu.edu/hpc/software/bioinf/fasta

07-Oct-2004

LION-XM

3.4t10

http://gears.aset.psu.edu/hpc/software/bioinf/fasta

03-Nov-2004

Versions listed in bold are the default version.


fastDNAml

Ribosomal Database Project

fastDNAml is an attempt to solve the same problem as DNAML (part of the PHYLIP package), but to do so faster and using less memory, so that larger trees and/or more bootstrap replicates become tractable.

fastDNAml is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

3.3

http://gears.aset.psu.edu/hpc/software/bioinf/fastdnaml

07-Oct-2004

LION-XM

3.3

http://gears.aset.psu.edu/hpc/software/bioinf/fastdnaml

03-Nov-2004

Versions listed in bold are the default version.


GeneMachine

National Human Genome Research Institute

GeneMachine is an integrated tool intended to perform both comparative and predictive gene identification techniques in a single run.

GeneM is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

0.23

http://gears.aset.psu.edu/hpc/software/bioinf/genem

07-Oct-2004

LION-XM

0.23

http://gears.aset.psu.edu/hpc/software/bioinf/genem

03-Nov-2004

Versions listed in bold are the default version.


GENSCAN

Christopher Burge

GENSCAN is a general-purpose gene identification program which analyzes genomic DNA sequences from a variety of organisms including human, other vertebrates, invertebrates and plants.

GENSCAN is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/genscan

20-Feb-2007

LION-XM

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/genscan

20-Feb-2007

Versions listed in bold are the default version.


HMMer

Washington University in St. Louis

Used to profile hidden Markov models.

HMMer is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

2.2g

http://gears.aset.psu.edu/hpc/software/bioinf/hmmer

07-Oct-2004

LION-XM

2.2g

http://gears.aset.psu.edu/hpc/software/bioinf/hmmer

03-Nov-2004

Versions listed in bold are the default version.


HMMgene

Center for Biological Sequence Analysis

HMMgene is a program for prediction of genes in anonymous DNA.

HMMgene is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

1.1e

http://gears.aset.psu.edu/hpc/software/bioinf/hmmgene

07-Oct-2004

LION-XM

1.1e

http://gears.aset.psu.edu/hpc/software/bioinf/hmmgene

03-Nov-2004

Versions listed in bold are the default version.


MrBayes

John P. Huelsenbeck and Fredrik Ronquist

MrBayes is a program for Bayesian inference of phylogeny using Markov Chain Monte Carlo methods.

MrBayes is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

2.01

http://gears.aset.psu.edu/hpc/software/bioinf/mrbayes

07-Oct-2004

LION-XM

2.01

http://gears.aset.psu.edu/hpc/software/bioinf/mrbayes

03-Nov-2004

Versions listed in bold are the default version.


MZEF

Cold Spring Harbor Laboratory

MZEF predicts internal coding exons in genomic DNA sequences. It allows users to predict putative internal protein coding exons, adjust prior probability and to output alternative overlapping exons.

MZEF is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/mzef

07-Oct-2004

LION-XM

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/mzef

03-Nov-2004

Versions listed in bold are the default version.


PHRED/PHRAP/Consed

Phil Green

PHRED/PHRAP/Consed | This software reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

PhPhC is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

0.000925.c

No on-line instructions available

07-Oct-2004

LION-XM

0.000925.c

No on-line instructions available

03-Nov-2004

Versions listed in bold are the default version.


PHYLIP

University of Washington Dept. of Genome Sciences

PHYLIP is a package of programs for inferring phylogenies.

PHYLIP is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

3.5c

http://gears.aset.psu.edu/hpc/software/bioinf/phylip

07-Oct-2004

LION-XM

3.5c

http://gears.aset.psu.edu/hpc/software/bioinf/phylip

03-Nov-2004

Versions listed in bold are the default version.


ReadSeq

Indiana University Dept. of Biology

Converts input DNA/AA sequence to specified format.

ReadSeq is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

2.1.7

http://gears.aset.psu.edu/hpc/software/bioinf/readseq

07-Oct-2004

LION-XM

2.1.7

http://gears.aset.psu.edu/hpc/software/bioinf/readseq

03-Nov-2004

Versions listed in bold are the default version.


RepeatMasker

Genetic Information Research Institute

Screens DNA sequences in fasta format against a library of repetitive elements and returns a masked query sequence ready for database searches as well as a table annotating the masked regions.

repeatmasker is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

20020713

http://gears.aset.psu.edu/hpc/software/bioinf/repeatmasker

07-Oct-2004

LION-XM

20020713

http://gears.aset.psu.edu/hpc/software/bioinf/repeatmasker

03-Nov-2004

Versions listed in bold are the default version.


SEG

National Center for Biotechnology Information

SEG divides sequences into contrasting segments of low-complexity and high-complexity.

SEG is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/seg

07-Oct-2004

LION-XM

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/seg

03-Nov-2004

Versions listed in bold are the default version.


sim4

Comp. Sci. and Engr. and Biochem. and Mol. Bio. at Penn State Univ.

sim4 is a similarity-based tool for aligning an expressed DNA sequence (EST, cDNA, mRNA) with a genomic sequence for the gene.

sim4 is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

20011012

http://gears.aset.psu.edu/hpc/software/bioinf/sim4

07-Oct-2004

LION-XM

20011012

http://gears.aset.psu.edu/hpc/software/bioinf/sim4

03-Nov-2004

Versions listed in bold are the default version.


Sputnik

University of Washington Dept. of Molecular Biotechnology

Sputnik is a C language program that searches DNA sequence files in Fasta format for microsatellite repeats. A sequence file is specified on the command line and the resulting hits are written to stdout along with their position in the sequence, length, and a score determined by the length of the repeat and the number of errors.

Sputnik is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/sputnik

07-Oct-2004

LION-XM

N/A

http://gears.aset.psu.edu/hpc/software/bioinf/sputnik

03-Nov-2004

Versions listed in bold are the default version.


Treetool

Ribosomal Database Project

Treetool is an interactive tool for displaying, editing, and printing phylogenetic trees.

Treetool is available on the following HPC machines:

Machine Version Instructions Last Update

LION-XL

2.0.2

http://gears.aset.psu.edu/hpc/software/bioinf/treetool

07-Oct-2004

LION-XM

2.0.2

http://gears.aset.psu.edu/hpc/software/bioinf/treetool

03-Nov-2004

Versions listed in bold are the default version.



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